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      產(chǎn)品展示您現(xiàn)在的位置: 首頁 > 產(chǎn)品展示 > > 美國(guó)戴安Dionex > 美國(guó)戴安 079930Dionex ProPac SCX and WCX Protein Column 生物色譜柱

      Dionex ProPac SCX and WCX Protein Column 生物色譜柱

      簡(jiǎn)要描述:

      戴安公司生產(chǎn)的儀器主要有離子色譜儀、高效液相色譜儀、快速溶劑萃取儀和氨基酸直接分析儀。其中離子色譜儀憑借著雄厚的技術(shù)優(yōu)勢(shì)和方法已廣泛地應(yīng)用于各個(gè)領(lǐng)域,其*達(dá)80%。與離子色譜相關(guān)的文章有90%均出自戴安公司生產(chǎn)的離子色譜儀。   
      戴安公司的快速溶劑萃取儀15分鐘之內(nèi)僅用15毫升溶劑既可完成對(duì)10g樣品的萃取,該技術(shù)已在環(huán)境、藥物、食品和聚合物工業(yè)等領(lǐng)域得到廣泛應(yīng)用。

      型號(hào) 美國(guó)戴安 079930
      廠商性質(zhì) 代理商
      更新日期 2018-04-16

      Strong and Weak Cation-Exchange Columns 

      for High-Resolution Separation of Proteins and MAbs

      New! The Thermo Scientific ProPac? SCX column line has expanded to include the next generation ProPac SCX-20 column. This column provides unequalled high resolution of protein variants.

      Please also see the Thermo Scientific MAbPac? SCX-10 column, a strong cation-exchange column designed specifically for high-resolution, high-efficiency analysis of monoclonal antibodies (MAbs) and associated variants. This column is complimentary to the industry-leading ProPac WCX-10 column for monoclonal antibody variant analysis. The MAbPac SCX-10 offers an alternative selectivity and provides higher resolution and efficiency for variant analysis of most monoclonal antibody samples than the ProPac WCX-10 column.

      ProPac SCX-10 and WCX-10 strong and weak cation-exchange columns are based on a nonporous core particle that results in high-efficiency peaks and high-resolution separations of protein variants. A hydrophilic layer prevents unwanted secondary interactions. A grafted cation-exchange surface provides pH-based selectivity control and fast mass transfer for high-efficiency separation and moderate capacity.

      • Characterization and quality control assessment of monoclonal antibodies and other proteins
      • Unequalled resolution
      • High-resolution separations with excellent sample recovery
      • Unmatched column-to-column and lot-to-lot reproducibility
      • Useful for characterization of related protein variants (e.g., deamidation and MAb lysine truncation variants)
      • Highly-efficient peaks with excellent sample recovery
      • Available in different dimensions and formats for flexibility in method development

      The ProPac SCX-10 is a strong cation-exchange column with sulfonate functional groups, and the ProPac WCX-10 column has a carboxylate functional group. Both are based on 10 ?m nonporous, polymeric beads and coated with a proprietary hydrophilic layer.

      All ProPac columns are manufactured and tested under the strictest specifications, resulting in unmatched column-to-column and lot-to-lot reproducibility. These columns are available as lot-select packages containing three columns from a single lot or three columns from three different lots, to assist quality control scientists in method validation.

      ProPac SCX-10 Strong Cation-Exchange Column for the High-Resolution Separation of Protein Isoforms  Specifications
      Maximum operating pressure3000 psi (21 MPa)
      Maximum operating temperature60 °C
      Recommended operating temperature: <40 °C
      Typical operating conditionsUV detection at 1 mL/min
      Recommended flow rate: 1 mL/min
      phase compatibilitypH 2–12; 80% compatible with acetonitrile, acetone, methanol.
      Compatible with nonionic and zwitterionic detergents.
      Incompatible with cationic detergents.
      Resin composition10-?m-diameter core bead (55% cross-linked) grafted with a pellicular layer to which are attached the sulfonate functional groups.
      Anion-exchange capacity< 100 ?g protein on-column, depending upon the protein
      (4 × 250 mm analytical column)
      Column constructionPEEK with 10-32 threaded ferrule-style end fittings.
      All components are nonmetallic.
      ProPac WCX-10 Weak Cation-Exchange Column for the High-Resolution Separation of Protein Isoforms  Specifications
      Resin composition10-?m-diameter core bead (55% cross-linked) grafted with a pellicular layer to which are attached the carboxylate functional groups.
      Anion-exchange capacity< 100 ?g protein on-column, depending upon the protein
      (4 × 250 mm analytical column)
      Column constructionPEEK with 10-32 threaded ferrule-style end fittings.
      All components are nonmetallic.
      Maximum operating pressure3000 psi (21 MPa)
      Maximum operating temperature60 °C
      Recommended operating temperature: <40 °C
      Typical operating conditionsUV detection at 1 mL/min
      Recommended flow rate: 1 mL/min
      phase compatibilitypH 2–12; 80% compatible with acetonitrile and acetone.
      Compatible with nonionic and zwitterionic detergents.
      Incompatible with cationic detergents.
      SCX Analytical Columns
      ProPac SCX-20 Analytical Column (4 x 250 mm)074628
      ProPac SCX-10 Analytical Column (4 x 250 mm)054995
      ProPac SCX-10 Analytical Column (2 x 250 mm)063456
      ProPac SCX-10 Semi-Preparative Column (9 x 250 mm)063700
      ProPac SCX-10 Semi-Preparative Column (22 x 250 mm)SP5522
      ProPac SCX-10 Lot Select Column Set (4 x 250 mm) (1 Lot of Resin)SP5727
      ProPac SCX-10 Lot Select Column Set (4 x 250 mm) (3 Lots of Resin)SP5728
      SCX Guard Columns
      ProPac SCX-20 Guard Column (4 x 50mm)074643
      ProPac SCX-10G Guard Column (4 x 50 mm)079930
      ProPac SCX-10G Guard Column (2 x 50 mm)063462
      WCX Analytical Columns
      ProPac WCX-10HT Analytical Column (4x 50mm)074600
      ProPac WCX-10 Analytical Column (4 x 100 mm)SP5829
      ProPac WCX-10 Analytical Column (4 x 150 mm)SP6703
      ProPac WCX-10 Analytical Column (4 x 250 mm)054993
      ProPac WCX-10 Lot Select 3 Column Set (4 x 250 mm) (1 Lot of Resin)SP5512
      ProPac WCX-10 Lot Select 3 Column Set (4 x 250 mm) (3 Lots of Resin)SP5513
      ProPac WCX-10 Analytical Column (2 x 250 mm)063472
      ProPac WCX-10 Semi-Preparative Column (9 x 250 mm)063474
      ProPac WCX-10 Semi-Preparative Column (22 x 250 mm)SP5482
      WCX Guard Columns
      ProPac WCX-10G Guard Column (2 x 50 mm)063480
      ProPac WCX-10G Guard Column (4 x 50 mm)054994

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